The Anti-CDH23 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0312) is a cutting-edge tool for research involving CDH23, a protein involved in cell adhesion and maintenance of sensory hair cells in the inner ear. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in a variety of applications, including Western blot and immunofluorescence.CDH23, also known as cadherin 23, plays a crucial role in the structure and function of hair cells in the cochlea, contributing to auditory signal transduction. Mutations in the CDH23 gene have been linked to various forms of hearing loss and balance disorders, making it a key target for studies in auditory neuroscience and genetic disorders.
The use of the Anti-CDH23 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0312) allows for precise detection and analysis of CDH23 expression levels in different cell types, providing valuable insights into its role in the development and maintenance of auditory function. Researchers studying hearing loss, deafness, and related conditions will find this antibody to be an essential tool in their investigations.
SKU:
HDAB0312
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC486
Synonyms:
BLAST-2; CD23; CD23A; CLEC4J; FCE2; IGEBF
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
