The Anti-CDH1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0310) offered by Assay Genie is a cutting-edge tool for researchers studying CDH1, a key protein involved in cell adhesion and signaling pathways. This antibody, generated using advanced technology, provides highly specific and sensitive detection of CDH1 in various biological samples.The Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0310) offers superior performance in applications such as immunohistochemistry and immunofluorescence, allowing for precise localization and visualization of CDH1 in tissues and cells. Its versatility and reliability make it an indispensable tool for studying the role of CDH1 in cancer metastasis, epithelial-mesenchymal transition, and other biological processes.
By using the Anti-CDH1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0310) from Assay Genie, researchers can gain valuable insights into the functions and mechanisms of CDH1, paving the way for new discoveries and potential therapeutic interventions in cancer and other diseases associated with aberrant CDH1 expression. Trust Assay Genie for high-quality antibodies that deliver exceptional results in your research endeavors.
SKU:
HDAB0310
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC484
Synonyms:
Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16. [provided by RefSeq, Nov 2015]