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CDC73 Rabbit Polyclonal Antibody (CAB0636)

SKU:
CAB0636
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CDC73
C1orf28
FIHP
HPTJT
HRPT1
HRPT2
HYX
€139 - €419
Frequently bought together:

Description

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Product Name:CDC73 Rabbit Polyclonal Antibody
SKU:CAB0636
Size:20uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 435-505 of human HRPT2 / CDC73 (Q6P1J9).
Sequence:MPQD WDRV VAVF VQGP AWQF KGWP WLLP DGSP VDIF AKIK AFHL KYDE VRLD PNVQ KWDV TVLE LSYH KRH
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:HYX; FIHP; HPTJT; HRPT1; HRPT2; C1orf28; HRPT2 / CDC73
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:61kDa
Observed MW:Refer to figures

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.

Purification Method:Affinity purification
Gene ID:79577
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from mouse testis, using HRPT2 / CDC73 Rabbit pAb (CAB0636).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.

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