The Anti-CDC40 Antibody (CAB19794) is a polyclonal antibody designed for research involving CDC40, a protein implicated in cell cycle regulation and DNA repair processes. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. It specifically binds to the CDC40 protein, enabling accurate detection and analysis in various cell types, making it an ideal tool for studies in molecular biology, cancer research, and genetic diseases.CDC40, also known as cell division cycle 40, plays a crucial role in ensuring accurate DNA replication and cell division.
Dysregulation of CDC40 has been linked to various diseases, including cancer and genetic disorders. By understanding the function and activity of CDC40, researchers can gain insights into the mechanisms underlying these conditions and potentially develop targeted therapies.Overall, the Anti-CDC40 Antibody (CAB19794) provides reliable and specific detection of CDC40 protein, making it a valuable tool for researchers investigating cell cycle regulation, DNA repair processes, and the role of CDC40 in disease pathology.
Product Name:
CDC40 Rabbit Monoclonal Antibody
SKU:
CAB19794
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDC40 (O60508).
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
Purification Method:
Affinity purification
Gene ID:
51362
Clone Number:
ARC2321
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CDC40 Rabbit mAb (CAB19794) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
