CDC25B Rabbit Monoclonal Antibody (CAB9758)
- SKU:
- CAB9758
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CDC25B
- cell division cycle 25B
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CDC25B Rabbit Monoclonal Antibody |
SKU: | CAB9758 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CDC25B (P30305). |
Sequence: | SSES SESS DAGL CMDS PSPM DPHM AEQT FEQA IQAA SRII RNEQ FAIR RFQS MPVR LLGH SPVL RNIT NSQA PDGR RKSE AGSG AASS SGED KEND GFVF K |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | CDC25B; cell division cycle 25B |
Positive Sample: | HeLa,Hep G2,Raji |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle pole. |
Calculated MW: | 65kDa |
Observed MW: | 60kDa |
CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist.
Purification Method: | Affinity purification |
Gene ID: | 994 |
Clone Number: | ARC1736 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |