CDC23 Rabbit Monoclonal Antibody (CAB6025)
- SKU:
- CAB6025
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ANAPC8
- APC8
- CUT23
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CDC23 Rabbit Monoclonal Antibody |
SKU: | CAB6025 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 498-597 of human CDC23 (Q9UJX2). |
Sequence: | YSCG EIVE HLEE STAF RYLA QYYF KCKL WDEA STCA QKCC AFND TREE GKAL LRQI LQLR NQGE TPTT EVPA PFFL PASL SANN TPTR RVSP LNLS SVTP |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | APC8; CUT23; ANAPC8; CDC23 |
Positive Sample: | HeLa,SKOV3,Mouse lung,Mouse brain,Mouse spleen,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleoplasm |
Calculated MW: | 69kDa |
Observed MW: | 69kDa |
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Purification Method: | Affinity purification |
Gene ID: | 8697 |
Clone Number: | ARC2133 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |