The CDC23 Polyclonal Antibody (CAB6025) is a valuable tool for researchers studying CDC23, a key player in the cell cycle regulation process. This antibody, produced in rabbits, is highly specific to human samples and is optimized for use in Western blot applications. By targeting the CDC23 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an essential component for studies related to cell division and cancer research.CDC23, also known as cell division cycle protein 23, is essential for proper progression through the cell cycle and is involved in the regulation of cell growth and division.
Dysregulation of CDC23 has been linked to various diseases, including cancers and genetic disorders, highlighting its importance as a potential therapeutic target. By utilizing the CDC23 Polyclonal Antibody, researchers can further investigate the roles of CDC23 in disease development and potentially identify new treatment strategies.
Product Name:
CDC23 Rabbit Monoclonal Antibody
SKU:
CAB6025
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 498-597 of human CDC23 (Q9UJX2).
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Purification Method:
Affinity purification
Gene ID:
8697
Clone Number:
ARC2133
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CDC23 Rabbit mAb (CAB6025) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
