The Anti-CD79B Antibody (CAB4362) is a valuable tool for research involving CD79B, a key protein involved in B-cell receptor signaling. This antibody, generated in rabbits, has high specificity for human samples and is validated for use in various applications, including Western blot and immunohistochemistry. By binding to the CD79B protein, this antibody enables researchers to detect and analyze CD79B expression in different cell types, making it ideal for studies in immunology and cancer research.CD79B, also known as B-cell antigen receptor complex-associated protein beta chain, is essential for B-cell development and activation.
Its role in B-cell receptor signaling makes it a critical target for investigating diseases like leukemia, lymphoma, and autoimmune disorders. Understanding the function of CD79B is crucial for developing targeted therapies that modulate B-cell activity in these disease contexts.Overall, the Anti-CD79B Antibody (CAB4362) provides researchers with a reliable tool to study CD79B expression and function, contributing to advancements in our understanding of B-cell biology and the development of novel therapeutic strategies for B-cell-related diseases.
Product Name:
CD79B Rabbit Monoclonal Antibody
SKU:
CAB4362
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD79B (P40259).
external side of plasma membrane, extracellular exosome, plasma membrane
Calculated MW:
26kDa
Observed MW:
30-50kDa
The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.
Purification Method:
Affinity purification
Gene ID:
974
Clone Number:
ARC52688
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using CD79B Rabbit mAb (CAB4362) at 1:3600 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
