The Anti-CD73 Recombinant Rabbit Monoclonal Antibody (HDAB0195) is a powerful tool for researchers studying CD73, an important cell surface enzyme involved in immune regulation and inflammation. This antibody, produced in rabbit cells, exhibits high reactivity with human samples and has been extensively validated for use in Western blot applications. By specifically binding to the CD73 protein, this antibody enables precise detection and analysis in a variety of cell types, making it ideal for investigations in immunology and cancer research.CD73, also known as ecto-5'-nucleotidase, plays a crucial role in regulating immune responses by converting extracellular adenosine monophosphate (AMP) to adenosine.
This process is essential for maintaining immune homeostasis and modulating inflammatory reactions. Research into CD73's function is critical for understanding its impact on diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. The insights gained from studying CD73 could lead to the development of novel therapies targeting this enzyme to modulate immune responses and combat disease progression.
SKU:
HDAB0195
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM204
Synonyms:
CD73,NT5E,5'-Nucleotidase,5'-NT,NT5,NTE
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
