The CD58 Monoclonal Antibody (CAB0806) is a valuable tool for researchers studying CD58, a cell adhesion molecule involved in immune responses. This antibody, produced in mice, is highly specific to human samples and has been validated for use in Western blot and flow cytometry applications. By binding to the CD58 protein, it allows for the detection and analysis of CD58 expression in various cell types, making it ideal for use in immunology research and studies on immune cell interactions.
CD58, also known as LFA-3, plays a crucial role in T cell activation and adhesion to antigen-presenting cells. Its involvement in immune responses makes it a key molecule to study in the context of diseases such as cancer, autoimmune disorders, and infectious diseases. Understanding the function and regulation of CD58 can provide valuable insights for the development of targeted therapies aimed at modulating immune responses and treating related conditions.
Product Name:
CD58 Rabbit Monoclonal Antibody
SKU:
CAB0806
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CD58 (P19256).
Cell membrane, GPI-anchor, Lipid-anchor, Single-pass type I membrane protein.
Calculated MW:
28kDa
Observed MW:
55-70kDa
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described.
Purification Method:
Affinity purification
Gene ID:
965
Clone Number:
ARC2540
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of K-562 cells, using CD58 antibody (CAB0806) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 10s.
