CD3E+CD3G Rabbit Monoclonal Antibody (CAB20213)
- SKU:
- CAB20213
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CD3E
- IMD18
- T3E
- TCRE
- CD3e molecule
- CD3G
- CD3-GAMMA
- IMD17
- T3G
- Research Area:
- Immunology
Description
Product Name: | CD3E+CD3G Rabbit Monoclonal Antibody |
SKU: | CAB20213 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-207(CD3E)& 1-182(CD3G) of human CD3 epsilon&CD3 gamma Heterodimer. |
Sequence: | MQSG THWR VLGL CLLS VGVW GQDG NEEM GGIT QTPY KVSI SGTT VILT CPQY PGSE ILWQ HNDK NIGG DEDD KNIG SDED HLSL KEFS ELEQ SGYY VCYP RGSK PEDA NFYL YLRA RVCE NCME MDVM SVAT IVIV DICI TGGL LLLV YYWS KNRK AKAK PVTR GAGA GGRQ RGQN KERP PPVP NPDY EPIR KGQR DLYS GLNQ RRI( CD3E )&ME QGKG LAVL ILAI ILLQ GTLA QSIK GNHL VKVY DYQE DGSV LLTC DAEA KNIT WFKD GKMI GFLT EDKK KWNL GSNA KDPR GMYQ CKGS QNKS KPLQ VYYR MCQN CIEL NAAT ISGF LFAE IVSI FVLA VGVY FIAG QDGV RQSR ASDK QTLL PNDQ LYQP LKDR EDDQ YSHL QGNQ LRRN (CD3 G) |
Tested Applications: | WB FC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 FC,1:500 - 1:1000 |
Synonyms: | CD3E; IMD18; T3E; TCRE; CD3e molecule; CD3G; CD3-GAMMA; IMD17; T3G; CD3E+CD3G |
Positive Sample: | Jurkat,MOLT-4 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Single-pass type I membrane protein, Membrane, Single-pass type I membrane protein. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
Purification Method: | Affinity purification |
Gene ID: | 916/917 |
Clone Number: | ARC5083-01 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |