CD3D Rabbit Monoclonal Antibody (CAB9770)
- SKU:
- CAB9770
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CD3-DELTA
- IMD19
- T3D
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | CD3D Rabbit Monoclonal Antibody |
SKU: | CAB9770 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 72-171 of human CD3D (P04234). |
Sequence: | RCNG TDIY KDKE STVQ VHYR MCQS CVEL DPAT VAGI IVTD VIAT LLLA LGVF CFAG HETG RLSG AADT QALL RNDQ VYQP LRDR DDAQ YSHL GGNW ARNK |
Tested Applications: | WB IF/ICC FC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 FC,1:50 - 1:200 |
Synonyms: | T3D; IMD19; CD3DELTA; CD3-DELTA; CD3D |
Positive Sample: | Jurkat |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type I membrane protein. |
Calculated MW: | 19kDa |
Observed MW: | 23kDa |
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Purification Method: | Affinity purification |
Gene ID: | 915 |
Clone Number: | ARC1741 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |