CD38 Rabbit Monoclonal Antibody (CAB20215)
- SKU:
- CAB20215
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CD38
- ADPRC 1
- ADPRC1
- Research Area:
- Cell Biology
Description
Product Name: | CD38 Rabbit Monoclonal Antibody |
SKU: | CAB20215 |
Size: | 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 43-300 of human CD38 (P28907). |
Sequence: | VPRW RQQW SGPG TTKR FPET VLAR CVKY TEIH PEMR HVDC QSVW DAFK GAFI SKHP CNIT EEDY QPLM KLGT QTVP CNKI LLWS RIKD LAHQ FTQV QRDM FTLE DTLL GYLA DDLT WCGE FNTS KINY QSCP DWRK DCSN NPVS VFWK TVSR RFAE AACD VVHV MLNG SRSK IFDK NSTF GSVE VHNL QPEK VQTL EAWV IHGG REDS RDLC QDPT IKEL ESII SKRN IQFS CKNI YRPD KFLQ CVKN PEDS SCTS EI |
Tested Applications: | FC ELISA |
Recommended Dilution: | FC,1:50 - 1:200 |
Synonyms: | ADPRC1; cADPR1; ADPRC 1; CD38 |
Conjugate: | Unconjugated |
Cellular Localization: | Membrane, Single-pass type II membrane protein. |
Calculated MW: | 34kDa |
Observed MW: | Refer to figures |
The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 952 |
Clone Number: | ARC5131-01 |
Storage Buffer: | Store at 4℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,pH7.3. |