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CD31/PECAM1 Rabbit Polyclonal Antibody (CAB20478)

SKU:
CAB20478
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CD31
Pecam
€139 - €419
Frequently bought together:

Description

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Product Name:CD31/PECAM1 Rabbit Polyclonal Antibody
SKU:CAB20478
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 611-678 of rat CD31/PECAM1 (NP_113779.1).
Sequence:YFLR KAKA KQKP VEMS RPAV PLLN SNSE KVSE PSVE TNSH YDSQ NMDV EYTE VEVS SLEP HQEN GRLP
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:CD31; Pecam; CD31/PECAM1
Positive Sample:Mouse lung,Mouse spleen,Mouse heart,Rat heart
Conjugate:Unconjugated
Cellular Localization:cell surface, cytoplasm, external side of plasma membrane, extracellular space, plasma membrane
Calculated MW:76kDa
Observed MW:130kDa

Enables protein phosphatase binding activity. Involved in several processes, including cellular response to interferon-gamma; negative regulation of GTPase activity; and negative regulation of actin filament polymerization. Located in cell surface and ruffle. Used to study pulmonary hypertension. Biomarker of bacterial pneumonia; orchitis; and osteoarthritis. Human ortholog(s) of this gene implicated in coronary artery disease (multiple); lung non-small cell carcinoma; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1).

Purification Method:Affinity purification
Gene ID:29583
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using CD31/PECAM1 antibody (CAB20478) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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