The Anti-CD30 Antibody (CAB9789) is a powerful tool for researchers studying CD30, a cell surface protein implicated in immune responses and inflammatory conditions. This polyclonal antibody, produced in rabbits, shows high reactivity towards human samples and is validated for use in Western blot applications. By specifically binding to the CD30 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an indispensable asset for studies in immunology and cancer research.CD30, also known as tumor necrosis factor receptor superfamily member 8 (TNFRSF8), plays a vital role in regulating immune responses and promoting inflammation.
Its involvement in various diseases, including cancer and autoimmune disorders, underscores the importance of studying its function and activity. The Anti-CD30 Antibody (CAB9789) provides researchers with a reliable tool for investigating CD30's role in immune regulation and disease development, paving the way for future therapeutic advancements in these areas.
Product Name:
CD30 Rabbit Monoclonal Antibody
SKU:
CAB9789
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 496-595 of human CD30 (P28908).
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Purification Method:
Affinity purification
Gene ID:
943
Clone Number:
ARC1750
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of A-549 cells, using CD30 antibody (CAB9789) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
