The CD239/BCAM Antibody (CAB19724) is a powerful tool for researchers studying CD239, a cell surface molecule involved in cell adhesion and migration processes. This polyclonal antibody, raised in rabbits, is highly specific and reacts strongly with human samples, making it a reliable choice for immunofluorescence and flow cytometry applications.CD239, also known as basal cell adhesion molecule (BCAM), plays a crucial role in cell interactions within the extracellular matrix, promoting cell adhesion and migration in various physiological and pathological contexts.
By targeting CD239 with this antibody, researchers can explore its function in processes like tissue development, wound healing, and cancer metastasis.This antibody is an essential tool for investigations into the molecular mechanisms underlying cell adhesion and migration, offering valuable insights into the role of CD239/BCAM in various cellular processes. With its high specificity and sensitivity, this antibody is an indispensable resource for studies in cell biology, developmental biology, and cancer research.
Product Name:
CD239/BCAM Rabbit Monoclonal Antibody
SKU:
CAB19724
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 529-628 of human CD239/BCAM (P50895).
This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4059
Clone Number:
ARC2252
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD239/BCAM Rabbit mAb (CAB19724) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
