The Anti-CD22 Biotinylated Recombinant Rabbit Monoclonal Antibody (HDAB0223) is a highly specific and sensitive tool for researchers studying CD22, a cell surface glycoprotein involved in B cell activation and differentiation. This antibody, produced in rabbits, has been validated for use in various applications, including immunohistochemistry and flow cytometry.CD22 is a critical regulator of B cell signaling and function, making it an important target for studies in immunology and oncology. The Anti-CD22 Antibody allows for the accurate detection and analysis of CD22 expression in different cell types, providing valuable insights into its role in normal and disease states.
By utilizing this antibody, researchers can further investigate the function of CD22 in various biological processes, such as B cell development, autoimmune disorders, and lymphoid malignancies. Its high specificity and sensitivity make it an indispensable tool for elucidating the complex mechanisms involving CD22, ultimately aiding in the development of targeted therapies and treatments for related diseases.
SKU:
HDAB0223
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM13
Synonyms:
SIGLEC-2, SIGLEC2
Applications:
ELISA, Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD22 include Refractory Hematologic Cancer and Hairy Cell Leukemia. Among its related pathways are Downstream signaling events of B Cell Receptor (BCR) and Hematopoietic cell lineage. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is SIGLEC2.
