The Anti-CD19 Recombinant Rabbit Monoclonal Antibody (HDAB0198) is a cutting-edge tool for research focused on CD19, a cell surface molecule essential for B cell development and function. This antibody, developed using rabbit monoclonal technology, offers high specificity and sensitivity for detecting CD19 in human samples. Validated for use in various applications such as Western blotting, this antibody binds specifically to the CD19 protein, enabling precise detection and analysis in a variety of cell types.CD19 is a key player in B cell biology, serving as a co-receptor for the B cell receptor and playing a critical role in B cell signaling and activation. Dysregulation of CD19 expression or function is associated with various B cell-related disorders, including leukemia and lymphoma.
Research into CD19 biology is crucial for advancing our understanding of B cell development and identifying new therapeutic targets for B cell-associated diseases.The Anti-CD19 Recombinant Rabbit Monoclonal Antibody (HDAB0198) is a valuable tool for scientists studying B cell biology, immunology, and cancer research. Its high specificity and reactivity with human samples make it an ideal choice for investigating the role of CD19 in health and disease. By using this antibody, researchers can gain valuable insights into the functions of CD19 and potentially develop novel strategies for targeting CD19-positive cells in various diseases.
SKU:
HDAB0198
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM207
Synonyms:
CD19,B4,CVID3,MGC12802
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
