The Anti-CD168/RHAMM Antibody (CAB2540) is a polyclonal antibody designed for research involving CD168/RHAMM, a cell surface protein associated with cell migration, adhesion, and proliferation. This antibody, raised in rabbits, is highly specific for human samples and is validated for use in various applications such as Western blot and immunohistochemistry.CD168/RHAMM, also known as receptor for hyaluronan-mediated motility, is involved in processes such as wound healing, cancer metastasis, and inflammation.
Its role in cell signaling and tumor progression makes it a crucial target for studies in cancer biology, tissue regeneration, and inflammatory diseases. The Anti-CD168/RHAMM Antibody enables researchers to detect and analyze the expression of this protein in different cell types, providing valuable insights into its function and potential therapeutic applications.
Product Name:
CD168/RHAMM Polyclonal Antibody
SKU:
CAB2540
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 341-440 of human CD168/RHAMM (NP_001136028.1).
HeLa,Mouse lung,Mouse spleen,Mouse small intestine,Mouse thymus,Rat testis
Conjugate:
Unconjugated
Cellular Localization:
Cell surface, Cytoplasm.
Calculated MW:
84kDa
Observed MW:
90kDa
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
3161
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD168/RHAMM Rabbit pAb (CAB2540) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
