The Anti-CD166 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0330) is a cutting-edge tool for researchers studying CD166, a cell surface protein involved in cell adhesion and signaling processes. This highly specific antibody, generated in rabbits, is optimized for use in various applications such as immunofluorescence, immunohistochemistry, and flow cytometry.CD166, also known as activated leukocyte cell adhesion molecule (ALCAM), plays a crucial role in cell migration, proliferation, and differentiation, making it a key player in processes like tissue development and wound healing.
Dysregulation of CD166 has been linked to diseases such as cancer, where its overexpression can enhance tumor cell invasion and metastasis.By using the Anti-CD166 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0330), researchers can accurately detect and analyze CD166 expression in different cell types and tissue samples. This antibody's high specificity and sensitivity make it an essential tool for studies in cancer biology, cell biology, and developmental biology, ultimately contributing to a better understanding of CD166's role in health and disease.
SKU:
HDAB0330
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC682
Synonyms:
CD166; MEMD
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011]
