The Anti-CD166/ALCAM Antibody (CAB9727) is a high-quality antibody designed for research involving CD166/ALCAM, a cell adhesion molecule with important functions in cell migration, adhesion, and signal transduction. This antibody, raised in rabbits, is highly specific for human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.CD166/ALCAM is known to play a key role in various physiological and pathological processes, including immune response, stem cell differentiation, and cancer progression. Its expression is often altered in different disease states, making it a potential biomarker for disease diagnosis and prognosis.
The Anti-CD166/ALCAM Antibody facilitates the detection and analysis of CD166/ALCAM protein levels in different cell types, making it a valuable tool for researchers in immunology, stem cell biology, and oncology.By understanding the function and regulation of CD166/ALCAM, researchers can gain insights into its role in disease development and progression, paving the way for the development of novel therapeutic strategies targeting this important cell adhesion molecule. Whether studying immune cell interactions, stem cell behavior, or cancer metastasis, the Anti-CD166/ALCAM Antibody is a powerful tool for advancing research in these areas.
Product Name:
CD166/ALCAM Rabbit Monoclonal Antibody
SKU:
CAB9727
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 484-583 of human CD166/ALCAM (Q13740).
Membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
65kDa
Observed MW:
100-105kDa
This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
Purification Method:
Affinity purification
Gene ID:
214
Clone Number:
ARC1720
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CD166/ALCAM Rabbit mAb (CAB9727) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
