The Anti-CD162 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0241) from Assay Genie is a cutting-edge tool for researchers studying CD162, a cell surface glycoprotein involved in immune cell function. This antibody, produced using innovative chimeric recombinant technology, offers enhanced specificity and sensitivity for detecting CD162 in human samples.CD162, also known as the P-selectin glycoprotein ligand-1 (PSGL-1), plays a vital role in immune cell adhesion and trafficking, making it a key player in inflammatory responses and immune surveillance. The Anti-CD162 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0241) is optimized for various applications, including immunohistochemistry, flow cytometry, and ELISA, providing researchers with a versatile tool for investigating CD162 expression and function.
With its high reactivity and specificity, this antibody enables precise detection and analysis of CD162 in a wide range of cell types and tissues, making it ideal for studies in immunology, inflammation, and vascular biology. By gaining insights into the role of CD162 in immune cell interactions, researchers can advance their understanding of immune-mediated diseases and develop targeted therapies for conditions such as inflammatory disorders and cancer.Overall, the Anti-CD162 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0241) offers researchers a reliable and robust tool for studying CD162
SKU:
HDAB0241
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC283
Synonyms:
PSGL-1,PSGL1,CD162,SELPLG,Selectin P ligand
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.
