null

CCR9 Rabbit Monoclonal Antibody (CAB9698)

SKU:
CAB9698
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CC-CKR-9
CDw199
GPR-9-6
GPR28
Research Area:
Immunology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:CCR9 Rabbit Monoclonal Antibody
SKU:CAB9698
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CCR9 (NP_112477.1).
Sequence:MTPT DFTS PIPN MADD YGSE STSS MEDY VNFN FTDF YCEK NNVR QFAS HFLP PLYW LVFI VGAL GNSL VILV YWYC TRVK TMTD MFLL NLAI ADLL FLVT
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:GPR28; CDw199; GPR-9-6; CC-CKR-9; CCR9
Positive Sample:A549,Jurkat,U-937,Mouse lung,Mouse spleen,Rat lung,Rat spleen
Conjugate:Unconjugated
Cellular Localization:Cell membrane
Calculated MW:42kDa
Observed MW:42kDa

The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:10803
Clone Number:ARC1706
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using CCR9 Rabbit mAb (CAB9698) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

Related Products