CCR9 Rabbit Monoclonal Antibody (CAB9698)
- SKU:
- CAB9698
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CC-CKR-9
- CDw199
- GPR-9-6
- GPR28
- Research Area:
- Immunology
Description
Product Name: | CCR9 Rabbit Monoclonal Antibody |
SKU: | CAB9698 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CCR9 (NP_112477.1). |
Sequence: | MTPT DFTS PIPN MADD YGSE STSS MEDY VNFN FTDF YCEK NNVR QFAS HFLP PLYW LVFI VGAL GNSL VILV YWYC TRVK TMTD MFLL NLAI ADLL FLVT |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | GPR28; CDw199; GPR-9-6; CC-CKR-9; CCR9 |
Positive Sample: | A549,Jurkat,U-937,Mouse lung,Mouse spleen,Rat lung,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10803 |
Clone Number: | ARC1706 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |