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Anti-CCR1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0291)

SKU:
HDAB0291
Product Type:
Rabbit Monoclonal Antibody
Antibody Type:
Monoclonal Antibody
Size:
100 μg
Reactivity:
Human
Host Species:
Rabbit
Antibody Isotype:
Rabbit/Human Fc chimeric IgG1
Clone:
DMC465
Synonyms:
CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
€675
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Description

system_update_altDatasheet
SKU:HDAB0291
Size:100 µg
Clonality:Monoclonal
Clone:DMC465
Synonyms:CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
Applications:Flow Cyt
Recommended Dilution:Flow Cyt 1:100
Host Species:Rabbit
Isotype:Rabbit/Human Fc chimeric IgG1
Reactivity:Human
Purification Method:Purified from cell culture supernatant by affinity chromatography
Formulation:Powder
Buffer:1XPBS
Storage:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:Research use only
Background:This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]

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