The Anti-CBR1 Antibody (CAB19263) is a essential tool for researchers studying the CBR1 protein, an enzyme involved in the metabolism of endocannabinoids and xenobiotics. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in applications such as Western blotting. By binding to the CBR1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it a valuable asset for studies in pharmacology and toxicology.CBR1, also known as cannabinoid receptor 1, plays a crucial role in the endocannabinoid system, which regulates various physiological processes including pain perception, mood, and appetite.
Furthermore, CBR1 is involved in the metabolism of exogenous compounds, making it a key player in drug metabolism and potentially influencing drug response and toxicity. Research into the function and regulation of CBR1 is essential for understanding its role in health and disease, and may lead to the development of novel therapeutic strategies targeting this enzyme.
Product Name:
CBR1 Rabbit Monoclonal Antibody
SKU:
CAB19263
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 178-277 of human CBR1 (P16152).
The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
873
Clone Number:
ARC2432
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CBR1 Rabbit mAb (CAB19263) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
