CASP1 Rabbit Polyclonal Antibody (CAB20470)
- SKU:
- CAB20470
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- IC
- ICE
- Il1
- Casp
- Il1bc
Frequently bought together:
Description
Product Name: | CASP1 Rabbit Polyclonal Antibody |
SKU: | CAB20470 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of mouse CASP1 (NP_033937.2). |
Sequence: | KVKE NLTA LEMV KEVK EFAA CPEH KTSD STFL VFMS HGIQ EGIC GTTY SNEV SDIL KVDT IFQM MNTL KCPS LKDK PKVI IIQA CRGE KQGV VLLK DSVR D |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | ICE; Il1bc; CASP1 |
Positive Sample: | Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | AIM2 inflammasome complex, cytoplasm, cytosol, extracellular region, extracellular space, inflammasome complex, IPAF inflammasome complex, mitochondrion, neuron projection, NLRP1 inflammasome complex, NLRP3 inflammasome complex, nucleus, plasma membrane |
Calculated MW: | 46kDa |
Observed MW: | 48kDa |
Enables cysteine-type endopeptidase activity. Involved in several processes, including positive regulation of I-kappaB kinase/NF-kappaB signaling; positive regulation of interleukin-1 beta production; and protein autoprocessing. Acts upstream of or within several processes, including membrane hyperpolarization; mitochondrial depolarization; and positive regulation of interleukin-1 alpha production. Located in extracellular region. Part of IPAF inflammasome complex. Is expressed in knee joint and metanephros. Orthologous to human CASP1 (caspase 1).
Purification Method: | Affinity purification |
Gene ID: | 12362 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |