Cardiac Troponin C Rabbit Monoclonal Antibody (CAB3816)
The Anti-Cardiac Troponin C Antibody (CAB3816) is a crucial tool for research involving cardiac troponin C, a protein found in cardiac muscle cells. This polyclonal antibody, generated in rabbits, is highly specific and reactive with human samples, making it an excellent choice for Western blot applications.Cardiac troponin C is a key component of the troponin complex, which plays a critical role in regulating muscle contraction in the heart. Elevated levels of cardiac troponin C in the blood are a well-established marker of cardiac injury, making it a valuable target for diagnostic and research purposes in cardiovascular disease.
By using the Anti-Cardiac Troponin C Antibody (CAB3816), researchers can accurately detect and quantify levels of cardiac troponin C in various sample types, providing valuable insights into cardiac function and disease pathology. This antibody is essential for studies investigating cardiac biomarkers, myocardial infarction, heart failure, and other cardiovascular conditions. Its high specificity and reliability make it a valuable tool for advancing research in cardiology and improving patient outcomes.
Product Name:
Cardiac Troponin C Rabbit Monoclonal Antibody
SKU:
CAB3816
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNNC1 (P63316).
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.
Purification Method:
Affinity purification
Gene ID:
7134
Clone Number:
ARC0840
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using TNNC1 Rabbit mAb (CAB3816) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
