The Anti-CAPG Antibody (CAB4413) is a highly specific tool for researchers studying CAPG, a protein involved in cell motility and actin filament organization. This monoclonal antibody, developed for use in various experimental applications, is generated in mice and exhibits strong reactivity with human samples. Validated for use in immunofluorescence, immunohistochemistry, and Western blotting, this antibody binds specifically to the CAPG protein, allowing for precise detection and analysis in a variety of cell types.CAPG, also known as gelsolin-like capping protein, plays a crucial role in regulating actin dynamics and facilitating cell migration, making it a key player in processes such as metastasis and tissue remodeling.
Its involvement in these cellular functions highlights its potential significance in cancer research and understanding diseases related to cell motility and invasion. Investigating the function and regulation of CAPG can provide valuable insights into the underlying mechanisms of these diseases, ultimately leading to the development of targeted therapies and interventions.
Product Name:
CAPG Rabbit Monoclonal Antibody
SKU:
CAB4413
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-188 of human CAPG (P40121).
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
822
Clone Number:
ARC2138
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CAPG Rabbit mAb (CAB4413) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
