CaMKII Rabbit Monoclonal Antibody (CAB0198)
- SKU:
- CAB0198
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CAM2
- CAMK2
- CAMKB
Frequently bought together:
Description
Product Name: | CaMKII Rabbit Monoclonal Antibody |
SKU: | CAB0198 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CaMKII (NP_741960.1). |
Sequence: | GVIL YILL VGYP PFWD EDQH RLYQ QIKA GAYD FPSP EWDT VTPE AKDL INKM LTIN PSKR ITAA EALK HPWI SHRS TVAS CMHR QETV DCLK KFNA RRKL K |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | CAM2; CAMK2; CAMKB; MRD54; CaMKIIbeta; CaMKII |
Positive Sample: | SH-SY5Y,U-251MG,Mouse brain,Rat brain,C6 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytoplasmic side, Peripheral membrane protein, Sarcoplasmic reticulum membrane, centrosome, cytoskeleton, microtubule organizing center. |
Calculated MW: | 73kDa |
Observed MW: | 50kDa/55kDa/60kDa |
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 816 |
Clone Number: | ARC1814 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |