Cadherin 16 Rabbit Monoclonal Antibody (CAB19644)
- SKU:
- CAB19644
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | Cadherin 16 Rabbit Monoclonal Antibody |
SKU: | CAB19644 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 50-180 of human Cadherin 16 (O75309). |
Sequence: | GAEG QIVL SGDS GKAT EGPF AMDP DSGF LLVT RALD REEQ AEYQ LQVT LEMQ DGHV LWGP QPVL VHVK DEND QVPH FSQA IYRA RLSR GTRP GIPF LFLE ASDR DEPG TANS DLRF HILS QAPA QPSP DMF |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | Ksp cadherin; Cadherin 16 |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Basolateral plasma membrane, extracellular exosome, Plasma membrane |
Calculated MW: | 90kDa |
Observed MW: | 120kDa |
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. Mapped to a previously identified cluster of cadherin genes on chromosome 16q22.1, the gene localizes with superfamily members CDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of an extracellular domain containing 6 cadherin domains, a transmembrane region and a truncated cytoplasmic domain but lacks the prosequence and tripeptide HAV adhesion recognition sequence typical of most classical cadherins. Expression is exclusively in kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Purification Method: | Affinity purification |
Gene ID: | 1014 |
Clone Number: | ARC2212 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |