The Anti-C-Maf Antibody (CAB3361) is a valuable tool for researchers studying the C-Maf protein, a transcription factor involved in the regulation of immune responses. Raised in rabbits, this antibody is highly specific to human samples and has been validated for use in Western blot applications. By binding to the C-Maf protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in immunology, oncology, and inflammatory diseases.C-Maf is known for its role in the differentiation and function of various immune cells, making it a key target for understanding the mechanisms underlying immune regulation.
Its dysregulation has been implicated in diseases such as cancer, autoimmune disorders, and inflammatory conditions. By studying the activity of C-Maf, researchers can gain insights that may lead to the development of novel therapies targeting immune function in these disease contexts.Overall, the Anti-C-Maf Antibody (CAB3361) provides researchers with a reliable tool for investigating the function and regulation of the C-Maf protein, offering potential insights into immune responses and diseases where this transcription factor plays a critical role.
Product Name:
c-Maf Rabbit Monoclonal Antibody
SKU:
CAB3361
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 274-373 of human c-Maf (O75444).
The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
4094
Clone Number:
ARC1954
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using c-Maf Rabbit mAb (CAB3361) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
