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c-Maf Rabbit Monoclonal Antibody (CAB3361)

SKU:
CAB3361
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
AYGRP
CCA4
CTRCT21
c-MAF
Research Area:
Epigenetics and Nuclear Signaling
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:c-Maf Rabbit Monoclonal Antibody
SKU:CAB3361
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 274-373 of human c-Maf (O75444).
Sequence:LNRQ LRGV SKEE VIRL KQKR RTLK NRGY AQSC RFKR VQQR HVLE SEKN QLLQ QVDH LKQE ISRL VRER DAYK EKYE KLVS SGFR ENGS SSDN PSSP EFFM
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:CCA4; AYGRP; c-MAF; CTRCT21; c-Maf
Positive Sample:293T,A-549,Raji,Mouse lung,Mouse kidney,Rat spleen,Rat kidney
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:38kDa
Observed MW:45kDa

The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:4094
Clone Number:ARC1954
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using c-Maf Rabbit mAb (CAB3361) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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