The Anti-Butyrylcholinesterase Antibody (CAB8861) offered by AssayGenie is a high-quality polyclonal antibody designed for research involving butyrylcholinesterase, an enzyme crucial for the regulation of acetylcholine levels in the nervous system. This antibody, produced using rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the butyrylcholinesterase protein, this antibody enables precise detection and analysis in various biological samples, making it an ideal tool for studies in neuroscience, pharmacology, and toxicology.Butyrylcholinesterase, also known as pseudocholinesterase, is an important enzyme involved in the metabolism of various compounds, including ester-containing drugs and toxins.
Dysregulation of butyrylcholinesterase activity has been linked to several neurological disorders, making it a promising target for therapeutic interventions. Research focusing on the role of butyrylcholinesterase in neurological diseases, drug metabolism, and environmental toxicity can benefit greatly from the use of this antibody.Overall, the Anti-Butyrylcholinesterase Antibody (CAB8861) provided by AssayGenie is a valuable tool for scientists and researchers interested in investigating the functions and mechanisms of butyrylcholinesterase in various physiological and pathological contexts. Its high specificity and sensitivity make it a reliable choice for
Product Name:
BCHE Rabbit Monoclonal Antibody
SKU:
CAB8861
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-602 of human Butyrylcholinesterase (P06276).
This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine.
Purification Method:
Affinity purification
Gene ID:
590
Clone Number:
ARC1328
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using Butyrylcholinesterase antibody (CAB8861) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
