The BSN Polyclonal Antibody (CAB20464) is a valuable tool for researchers studying BSN, a protein associated with synaptic vesicle endocytosis and neurotransmitter release. This antibody, generated in rabbits, exhibits strong reactivity with human samples and is optimized for Western blotting applications. By specifically binding to the BSN protein, this antibody enables the detection and analysis of BSN expression in various cell types, making it an ideal choice for investigations in neuroscience and neurodegenerative diseases.BSN plays a critical role in regulating synaptic transmission and plasticity, making it a key player in neuronal communication and brain function.
Dysregulation of BSN has been implicated in various neurological disorders, including Alzheimer's disease and Parkinson's disease. By studying the function and expression of BSN, researchers can gain insights into the underlying mechanisms of these conditions and develop potential therapeutic interventions targeting BSN-related pathways.Overall, the BSN Polyclonal Antibody (CAB20464) offers researchers a reliable tool for investigating the role of BSN in synaptic function and neurodegenerative diseases, ultimately paving the way for advancements in neuroscience research and drug development.
Product Name:
BSN Rabbit Polyclonal Antibody
SKU:
CAB20464
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 830-950 of human BSN (NP_003449.2).
Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses.
Purification Method:
Affinity purification
Gene ID:
8927
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunofluorescence analysis of Neuro-2a cells using BSN Rabbit pAb (CAB20464) at dilution of 1:50 (40x lens). Blue: DAPI for nuclear staining.
