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[KO Validated] BRD4 Rabbit Polyclonal Antibody (CAB18839)

SKU:
CAB18839
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
BRD4
CAP
HUNK1
HUNKI
MCAP
Research Area:
Epigenetics and Nuclear Signaling
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] BRD4 Rabbit Polyclonal Antibody
SKU:CAB18839
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 650-722 of human BRD4 (NP_055114.1).
Sequence:DEIE IDFE TLKP STLR ELER YVTS CLRK KRKP QAEK VDVI AGSS KMKG FSSS ESES SSES SSSD SEDS ETGP A
Tested Applications:WB ELISA
Recommended Dilution:WB,1:100 - 1:500
Synonyms:CAP; MCAP; HUNK1; HUNKI; FSHRG4; D4
Positive Sample:HeLa,293T,Jurkat,C6
Cellular Localization:Chromosome, Nucleus.
Calculated MW:152kDa
Observed MW:120kDa

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

Purification Method:Affinity purification
Gene ID:23476
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using [KO Validated] BRD4 Rabbit pAb (CAB18839) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 300s.

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