Brachyury Rabbit Monoclonal Antibody (CAB5078)
- SKU:
- CAB5078
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- SAVA
- TFT
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | Brachyury Rabbit Monoclonal Antibody |
SKU: | CAB5078 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 266-435 of human Brachyury (O15178). |
Sequence: | GALS LPST HSCD RYPT LRSH RSSP YPSP YAHR NNSP TYSD NSPA CLSM LQSH DNWS SLGM PAHP SMLP VSHN ASPP TSSS QYPS LWSV SNGA VTPG SQAA AVSN GLGA QFFR GSPA HYTP LTHP VSAP SSSG SPLY EGAA AATD IVDS QYDA AAQG RLIA SWTP VSPP SM |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | T; TFT; SAVA; Brachyury |
Positive Sample: | NCI-H460,Mouse brain,Mouse thymus,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 47kDa |
Observed MW: | 49kDa |
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies.
Purification Method: | Affinity purification |
Gene ID: | 6862 |
Clone Number: | ARC1983 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |