The BNIP1 Polyclonal Antibody (CAB4405) is a valuable tool for researchers studying BNIP1, a protein involved in various cellular processes, including apoptosis and autophagy. This antibody, raised in rabbits, is highly specific to human samples and is validated for use in Western blot applications.BNIP1, also known as Bcl-2/adenovirus E1B 19 kDa protein-interacting protein 1, plays a critical role in regulating cell death and survival pathways. Its interaction with Bcl-2 family members and involvement in mitochondrial dynamics make it a key player in cancer biology and neurodegenerative diseases.
The BNIP1 antibody allows for the detection and analysis of BNIP1 protein levels in different cell types, providing valuable insights into its function in health and disease.Researchers studying apoptosis, autophagy, and mitochondrial function will find the BNIP1 Polyclonal Antibody an essential tool for their experiments. By understanding the role of BNIP1 in cellular processes, novel therapeutic targets for cancer and neurodegenerative disorders may be identified, leading to the development of new treatment strategies.
Product Name:
BNIP1 Rabbit Monoclonal Antibody
SKU:
CAB4405
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human BNIP1 (Q12981).
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. In addition, this protein is involved in vesicle transport into the endoplasmic reticulum. Alternative splicing of this gene results in four protein products with identical N- and C-termini.
Purification Method:
Affinity purification
Gene ID:
662
Clone Number:
ARC2137
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using BNIP1 Rabbit mAb (CAB4405) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
