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β1-Adrenergic Receptor Polyclonal Antibody (CAB20818)

SKU:
CAB20818
Product Type:
Antibody
Antibody Type:
Secondary Antibody
Host Species:
Goat
Isotype:
IgG
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:β1-Adrenergic Receptor Polyclonal Antibody
SKU:CAB20818
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 350-450 of human β1-Adrenergic Receptor (NP_000675.1).
Sequence:HREL VPDR LFVF FNWL GYAN SAFN PIIY CRSP DFRK AFQG LLCC ARRA ARRR HATH GDRP RASG CLAR PGPP PSPG AASD DDDD DVVG ATPP ARLL EPWA G
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:RHR; B1AR; FNSS2; ADRB1R; BETA1AR; β1-Adrenergic Receptor
Positive Sample:A-549,Mouse heart,Rat heart
Conjugate:Unconjugated
Cellular Localization:early endosome, neuronal dense core vesicle, plasma membrane, Schaffer collateral - CA1 synapse
Calculated MW:51kDa
Observed MW:50kDa

The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.

Purification Method:Affinity purification
Gene ID:153
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using β1-Adrenergic Receptor Rabbit pAb (CAB20818) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.

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