The Anti-Beta1-Adrenergic Receptor Antibody (CAB20818) is a valuable tool for research involving the beta1-adrenergic receptor, a key component in the sympathetic nervous system responsible for regulating heart rate and contractility. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.The beta1-adrenergic receptor is involved in numerous physiological processes, including cardiac function and smooth muscle relaxation. Dysregulation of this receptor has been implicated in various cardiovascular diseases, making it a target of interest in cardiovascular research.
By binding specifically to the beta1-adrenergic receptor, this antibody enables the detection and analysis of this important protein in a variety of cell types.Researchers studying cardiac function, heart disease, and the sympathetic nervous system will find the Anti-Beta1-Adrenergic Receptor Antibody to be a valuable asset in their experiments. Understanding the role of the beta1-adrenergic receptor in health and disease can lead to the development of novel therapeutic strategies for cardiovascular disorders.
Product Name:
β1-Adrenergic Receptor Polyclonal Antibody
SKU:
CAB20818
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human β1-Adrenergic Receptor (NP_000675.1).
The adrenergic receptors (subtypes alpha 1, alpha 2, beta 1, and beta 2) are a prototypic family of guanine nucleotide binding regulatory protein-coupled receptors that mediate the physiological effects of the hormone epinephrine and the neurotransmitter norepinephrine. Beta-1 adrenoceptors are predominately located in the heart. Specific polymorphisms in this gene have been shown to affect the resting heart rate and can be involved in heart failure.
Purification Method:
Affinity purification
Gene ID:
153
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using β1-Adrenergic Receptor Rabbit pAb (CAB20818) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
