The Anti-Beclin-1 Antibody (CAB7353) is a highly specific and reliable tool for researchers studying autophagy and cell biology. Beclin-1 is a key regulator of the autophagy process, involved in the degradation and recycling of cellular components. This antibody, validated for knockout (KO) experiments, is ideal for Western blot and immunohistochemistry applications in human samples.Beclin-1 plays a crucial role in maintaining cellular homeostasis and has been implicated in a variety of human diseases, including cancer, neurodegenerative disorders, and infectious diseases.
By targeting Beclin-1 with this antibody, researchers can better understand its function and potential therapeutic applications in these pathologies.With its high reactivity and specificity, the Anti-Beclin-1 Antibody (CAB7353) is a valuable tool for researchers investigating autophagy-related processes and their implications in various disease states.
This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8678
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using [KO Validated] Beclin 1 Rabbit pAb (CAB7353) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
