The Anti-BCMA Biotinylated Recombinant Rabbit Monoclonal Antibody (HDAB0219) is a cutting-edge tool for researchers studying B-cell maturation antigen (BCMA), a cell surface receptor involved in B-cell development and survival. This antibody, produced in rabbits, offers high specificity and sensitivity for detecting BCMA in human samples, making it a reliable choice for various research applications such as immunohistochemistry and flow cytometry.BCMA is a key target in the development of novel therapies for multiple myeloma, a type of blood cancer characterized by the abnormal growth of plasma cells. By targeting BCMA, researchers aim to disrupt the survival signals in myeloma cells, leading to their elimination. The Anti-BCMA Biotinylated Recombinant Rabbit Monoclonal Antibody enables precise detection and analysis of BCMA expression in cell lines and tissue samples, facilitating the investigation of BCMA-targeted treatments for multiple myeloma and other B-cell-related diseases.
With its exceptional performance and versatility, this antibody holds great promise for advancing our understanding of BCMA biology and supporting the development of targeted therapies for BCMA-expressing cancers. Researchers can rely on the Anti-BCMA Biotinylated Recombinant Rabbit Monoclonal Antibody (HDAB0219) to fuel their investigations into the role of BCMA in cancer progression and to drive innovation in precision medicine approaches for cancer treatment.
SKU:
HDAB0219
Size:
100 µg
Clonality:
Monoclonal
Clone:
DM6
Synonyms:
TNFRSF17
Applications:
ELISA, Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit IgG
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
