The Anti-AUTS2 Antibody (CAB20477) is a highly specialized tool for researchers studying AUTS2, a gene associated with neurodevelopmental disorders. This antibody, produced in rabbits, is specifically designed to target AUTS2 protein and is validated for use in various experimental techniques, such as Western blotting. By binding to AUTS2, this antibody allows for the detection and analysis of AUTS2 protein levels in different cell types, making it an essential tool for studies in neuroscience and genetic disorders.AUTS2, also known as Autism Susceptibility Candidate 2, plays a crucial role in brain development and function, and dysregulation of this gene has been linked to conditions such as autism spectrum disorder and intellectual disabilities.
Research into the function of AUTS2 is essential for unraveling the mechanisms underlying these disorders and exploring potential therapeutic interventions. By using the Anti-AUTS2 Antibody, researchers can gain valuable insights into the role of AUTS2 in neurodevelopmental processes and potentially uncover new avenues for treatment development.
Product Name:
AUTS2 Rabbit Polyclonal Antibody
SKU:
CAB20477
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 550-770 of human AUTS2 (NP_001120703).
This gene has been implicated in neurodevelopment and as a candidate gene for numerous neurological disorders, including autism spectrum disorders, intellectual disability, and developmental delay. Mutations in this gene have also been associated with non-neurological disorders, such as acute lymphoblastic leukemia, aging of the skin, early-onset androgenetic alopecia, and certain cancers. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
26053
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using AUTS2 Rabbit pAb (CAB20477) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 300s.
