Anti-ATP6V1F Antibody (CAB20247)
- SKU:
- CAB20247
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- VATF
- Vma7
- ATP6S14
Frequently bought together:
Description
| Product Name: | ATP6V1F Rabbit pAb |
| Product Code: | CAB20247 |
| Size: | 50uL, 100uL |
| Synonyms: | VATF, Vma7, ATP6S14 |
| Applications: | WB |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human ATP6V1F (NP_004222.2). |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-119 of human ATP6V1F (NP_004222.2). |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 9296 |
| Uniprot: | Q16864 |
| Calculated MW: | 13kDa |
| Observed MW: | Refer to figures |
| UniProt Protein Function: | ATP6V1F: Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. Belongs to the V-ATPase F subunit family. Protein type: Hydrolase Chromosomal Location of Human Ortholog: 7q32 Cellular Component: cytosol; membrane; vacuolar proton-transporting V-type ATPase complex Molecular Function: ATPase activity, coupled to transmembrane movement of ions; protein binding Biological Process: insulin receptor signaling pathway; transferrin transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16864 |
| NCBI GenInfo Identifier: | 126302612 |
| NCBI Gene ID: | 9296 |
| NCBI Accession: | Q16864.2 |
| UniProt Secondary Accession: | Q16864,Q6IBA8, C9J2K4 |
| UniProt Related Accession: | Q16864 |
| Molecular Weight: | 16,402 Da |
| NCBI Full Name: | V-type proton ATPase subunit F |
| NCBI Synonym Full Names: | ATPase H+ transporting V1 subunit F |
| NCBI Official Symbol: | ATP6V1FÂ Â |
| NCBI Official Synonym Symbols: | VATF; Vma7; ATP6S14Â Â |
| NCBI Protein Information: | V-type proton ATPase subunit F |
| UniProt Protein Name: | V-type proton ATPase subunit F |
| UniProt Synonym Protein Names: | V-ATPase 14 kDa subunit; Vacuolar proton pump subunit F |
| Protein Family: | |
| UniProt Gene Name: | ATP6V1FÂ Â |
| UniProt Entry Name: | VATF_HUMAN |
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