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ATP1B3 Rabbit Monoclonal Antibody (CAB19637)

SKU:
CAB19637
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ATPB-3
CD298
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ATP1B3 Rabbit Monoclonal Antibody
SKU:CAB19637
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 180-279 of human ATP1B3 (P54709).
Sequence:GLKP EGVP RIDC VSKN EDIP NVAV YPHN GMID LKYF PYYG KKLH VGYL QPLV AVQV SFAP NNTG KEVT VECK IDGS ANLK SQDD RDKF LGRV MFKI TARA
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200
Synonyms:CD298; ATPB-3; ATP1B3
Positive Sample:293T,U-87MG,Mouse lung,Mouse testis,Mouse brain,Rat lung,Rat testis,Rat spleen
Conjugate:Unconjugated
Cellular Localization:apical plasma membrane, basolateral plasma membrane, extracellular exosome, melanosome, plasma membrane, sperm flagellum
Calculated MW:22kDa/32kDa
Observed MW:32-45kDa

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.

Purification Method:Affinity purification
Gene ID:483
Clone Number:ARC2205
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ATP1B3 Rabbit mAb (CAB19637) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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