ATP1A2 Rabbit Monoclonal Antibody (CAB19278)
- SKU:
- CAB19278
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ATP1A2
- FHM2
- MHP2
- ATPase Na+/K+ transporting subunit alpha 2
Description
Product Name: | ATP1A2 Rabbit Monoclonal Antibody |
SKU: | CAB19278 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ATP1A2 (P50993). |
Sequence: | MGRG AGRE YSPA ATTA ENGG GKKK QKEK ELDE LKKE VAMD DHKL SLDE LGRK YQVD LSKG LTNQ RAQD VLAR DGPN ALTP PPTT PEWV KFCR QLFG GFSI |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | FHM2; MHP2; DEE98; FARIMPD; ATP1A2 |
Positive Sample: | Mouse heart,Mouse skeletal muscle,Rat heart |
Conjugate: | Unmodified |
Cellular Localization: | Cell membrane, Membrane, Multi-pass membrane protein. |
Calculated MW: | 112kDa |
Observed MW: | 100kDa |
The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood.
Purification Method: | Affinity purification |
Gene ID: | 477 |
Clone Number: | ARC2458 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |