The ARPC2 Polyclonal Antibody (CAB1382) is specifically designed for research involving ARPC2, a key component of the Arp2/3 complex that plays a critical role in actin filament nucleation and branching. The antibody, raised in rabbits, has high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications.ARPC2 is essential for various cellular processes, including cell motility, endocytosis, and cytokinesis. Dysregulation of ARPC2 has been implicated in diseases such as cancer, where aberrant actin dynamics contribute to tumor growth and metastasis.
By targeting ARPC2, researchers can gain insights into actin cytoskeleton regulation and potentially develop novel therapeutic strategies for cancer treatment.Overall, the ARPC2 Polyclonal Antibody (CAB1382) is a valuable tool for researchers studying actin dynamics, cell motility, and cancer biology. Its specificity and sensitivity make it ideal for investigating the role of ARPC2 in cellular processes and disease progression.
Product Name:
ARPC2 Rabbit Monoclonal Antibody
SKU:
CAB1382
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ARPC2 (O15144).
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
Purification Method:
Affinity purification
Gene ID:
10109
Clone Number:
ARC2558
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARPC2 Rabbit mAb (CAB1382) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
