Aromatase Rabbit Monoclonal Antibody (CAB12238)
- SKU:
- CAB12238
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ARO
- ARO1
- CPV1
- CYAR
- CYP19
- CYPXIX
- P-450AROM
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Aromatase Rabbit Monoclonal Antibody |
SKU: | CAB12238 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Aromatase (CYP19A1) (P11511). |
Sequence: | MVLE MLNP IHYN ITSI VPEA MPAA TMPV LLLT GLFL LVWN YEGT SSIP GPGY CMGI GPLI SHGR FLWM GIGS ACNY YNRV YGEF MRVW ISGE ETLI ISKS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM; Aromatase (CYP19A1) |
Positive Sample: | U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | endoplasmic reticulum |
Calculated MW: | 58kDa |
Observed MW: | 58kDa |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities.
Purification Method: | Affinity purification |
Gene ID: | 1588 |
Clone Number: | ARC0635 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |