The Anti-Arginase 2 (ARG2) Antibody (CAB19233) is a valuable tool for research involving Arginase 2, an enzyme that plays a crucial role in the urea cycle and in regulating nitric oxide production. The antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. It specifically binds to the ARG2 protein, allowing for accurate detection and analysis in various cell types, making it ideal for studies in metabolism, immunology, and cancer research.
Arginase 2 is involved in the metabolism of arginine and has been linked to various diseases such as cancer, cardiovascular disorders, and metabolic syndromes. Understanding the activity of ARG2 is essential for unraveling its role in these diseases and for the development of potential therapies targeting this enzyme. The Anti-Arginase 2 Antibody provides researchers with a reliable tool to study the function of ARG2 and its implications in health and disease.
Product Name:
Arginase 2 (ARG2) Rabbit Monoclonal Antibody
SKU:
CAB19233
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 255-354 of human Arginase 2 (ARG2) (P78540).
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.
Purification Method:
Affinity purification
Gene ID:
384
Clone Number:
ARC2391
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from 293T cells, using Arginase 2 (ARG2) Rabbit mAb (CAB19233) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
