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Arginase 2 (ARG2) Rabbit Monoclonal Antibody (CAB19233)

SKU:
CAB19233
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ARG2
arginase 2
Research Area:
Immunology
$167 - $503
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Arginase 2 (ARG2) Rabbit Monoclonal Antibody
SKU:CAB19233
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 255-354 of human Arginase 2 (ARG2) (P78540).
Sequence:FDPT LAPA TGTP VVGG LTYR EGMY IAEE IHNT GLLS ALDL VEVN PQLA TSEE EAKT TANL AVDV IASS FGQT REGG HIVY DQLP TPSS PDES ENQA RVRI
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:ARG2; arginase 2; Arginase 2 (ARG2)
Positive Sample:293T
Conjugate:Unconjugated
Cellular Localization:Mitochondrion
Calculated MW:39kDa
Observed MW:40kDa

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described.

Purification Method:Affinity purification
Gene ID:384
Clone Number:ARC2391
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from 293T cells, using Arginase 2 (ARG2) Rabbit mAb (CAB19233) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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