The Anti-ARF5 Antibody (CAB3382) is a high-quality polyclonal antibody specifically designed for research involving ARF5, a small GTPase protein involved in various cellular processes such as membrane trafficking and cytoskeleton remodeling. This antibody, generated in rabbits, has been validated for use in applications like immunocytochemistry and immunofluorescence to detect and study ARF5 expression in different cell types.ARF5, a member of the ARF protein family, plays a crucial role in regulating vesicle formation and transport within cells, making it an important target for studying cellular trafficking pathways. Dysregulation of ARF5 function has been implicated in diseases such as cancer, neurodegenerative disorders, and infectious diseases.
Understanding the role of ARF5 in these contexts can provide valuable insights for developing targeted therapies or interventions.By using the Anti-ARF5 Antibody (CAB3382) in your research, you can accurately detect and analyze ARF5 expression, allowing for in-depth investigation into its cellular functions and potential implications in disease pathways. This antibody is a valuable tool for scientists working in cell biology, molecular biology, and drug discovery, looking to uncover the intricacies of ARF5-mediated processes and their impact on health and disease.
Product Name:
ARF5 Rabbit Monoclonal Antibody
SKU:
CAB3382
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 81-180 of human ARF5 (P84085).
This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization.
Purification Method:
Affinity purification
Gene ID:
381
Clone Number:
ARC1960
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using ARF5 Rabbit mAb (CAB3382) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
