APOE Rabbit Polyclonal Antibody (CAB0304)
- SKU:
- CAB0304
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | APOE Rabbit Polyclonal Antibody |
SKU: | CAB0304 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 41-307 of human APOE (NP_000032.1). |
Sequence: | GQRW ELAL GRFW DYLR WVQT LSEQ VQEE LLSS QVTQ ELRA LMDE TMKE LKAY KSEL EEQL TPVA EETR ARLS KELQ AAQA RLGA DMED VCGR LVQY RGEV QAML GQST EELR VRLA SHLR KLRK RLLR DADD LQKR LAVY QAGA REGA ERGL SAIR ERLG PLVE QGRV RAAT VGSL AGQP LQER AQAW GERL RARM EEMG SRTR DRLD EVKE QVAE VRAK LEEQ AQQI RLQA EAFQ ARLK SWFE PLVE DMQR QWAG LVEK VQAA VGT |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | AD2; LPG; APO-E; ApoE4; LDLCQ5; APOE |
Positive Sample: | SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 36kDa |
Observed MW: | 35kDa |
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Purification Method: | Affinity purification |
Gene ID: | 348 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |